When cancer spreads to the cerebrospinal fluid surround the brain and spinal cord and/or the lining of the brain and spinal cord, it causes an aggressive disease called leptomeningeal disease, or LMD.
It is also known as leptomeningeal carcinomatosis, leptomeningeal disease (LMD), leptomeningeal metastasis, meningeal metastasis and meningeal carcinomatosis. It occurs with cancers that are most likely to spread to the central nervous system. [6]